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Modafinil https://allmodafinil.com/ also uses orexin which is found in the hypothalamus but is transmitted to various parts of the brain. Activating orexin can also lead to increased levels of dopamine and norepinephrine. Norepinephrine also increases in the ventrolateral preoptic nucleus leading to a rapid response to stressful activities. Similarly, the drug is responsible for elevating mood as it increases the level of serotonin in the frontal cortex.

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